abstract：BACKGROUND:Quality improvement (QI) is a central tenant of trauma center accreditation in most countries, but its effectiveness is largely unknown. We sought to explore opportunities for improving trauma QI. METHODS:We performed a qualitative research study using grounded theory analyses of interviews with medical dir...

journal_title：Journal of critical care

authors： Santana MJ,Straus S,Gruen R,Stelfox HT

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:To discharge a patient from the intensive care unit (ICU) is a complex decision-making process because in-hospital mortality after critical illness may be as high as up to 27%. Static C-reactive protein (CRP) values have been previously evaluated as a predictor of post-ICU mortality with conflicting results. Th...

journal_title：Journal of critical care

authors： Ranzani OT,Prada LF,Zampieri FG,Battaini LC,Pinaffi JV,Setogute YC,Salluh JI,Povoa P,Forte DN,Azevedo LC,Park M

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate the role of inflammatory biomarkers and total bile acid (TBA) in oral secretions in the development of ventilator-associated pneumonia (VAP). MATERIALS:This prospective study was conducted in an intensive care unit. Oral secretions were collected from mechanically venti...

journal_title：Journal of critical care

authors： Tsai HC,Lin FC,Chen YC,Chang SC

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:Acute kidney injury (AKI) is a common source of morbidity after trauma. We sought to determine novel risk factors for AKI, by Acute Kidney Injury Network (AKIN) criteria, in critically ill trauma patients. MATERIALS AND METHODS:A prospective cohort of 400 patients admitted to the intensive care unit of a level...

journal_title：Journal of critical care

authors： Shashaty MG,Meyer NJ,Localio AR,Gallop R,Bellamy SL,Holena DN,Lanken PN,Kaplan S,Yarar D,Kawut SM,Feldman HI,Christie JD

更新日期：2012-10-01 00:00:00

abstract：INTRODUCTION:The pathophysiology of sepsis-associated encephalopathy (SAE) is not entirely clear, but one of the possible underlying mechanisms is the alteration of the cerebral microvascular function. The aim of the present work was to test whether cerebral vasomotor reactivity is impaired in patients with severe seps...

journal_title：Journal of critical care

authors： Fülesdi B,Szatmári S,Antek C,Fülep Z,Sárkány P,Csiba L,Molnár C

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:The aim of the present study was to describe the variation in adiponectin and resistin levels, 2 adipokines with opposing effects on metabolism, in mechanically ventilated patients with sepsis and their relationships to disease severity and cytokine levels. MATERIALS AND METHODS:An observational prospective st...

journal_title：Journal of critical care

authors： Vassiliadi DA,Tzanela M,Kotanidou A,Orfanos SE,Nikitas N,Armaganidis A,Koutsilieris M,Roussos C,Tsagarakis S,Dimopoulou I

更新日期：2012-08-01 00:00:00

abstract：:Neurosurgical patients commonly require mechanical ventilation and monitoring in a neurocritical care unit. There are only few studies that specifically address the process of liberation from mechanical ventilation in this population. Patients who remain ventilator or artificial airway dependent receive a tracheostomy...

journal_title：Journal of critical care

authors： Lazaridis C,DeSantis SM,McLawhorn M,Krishna V

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:Multiple equations exist for predicting resting energy expenditure (REE). The accuracy of these for estimating energy requirements of critically ill patients is not clear, especially for obese patients. We sought to compare REE, calculated with published formulas, with measured REE in a cohort of mechanically v...

journal_title：Journal of critical care

authors： Kross EK,Sena M,Schmidt K,Stapleton RD

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:Urinary excretion of chloride corrects metabolic acidosis, but this may be hampered in patients with impaired renal function. We explored the effects of renal function on acid-base characteristics and urinary strong ion excretion using the Stewart approach in critically ill patients with metabolic acidosis. MA...

journal_title：Journal of critical care

authors： Moviat M,Terpstra AM,van der Hoeven JG,Pickkers P

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:The ability of the global end-diastolic volume index (GEDVI) and respiratory variations in left ventricular outflow tract velocity (ΔVTI(LVOT)) for prediction of fluid responsiveness is still under debate. The aim of the present study was to challenge the predictive power of GEDVI and ΔVTI(LVOT) compared with p...

journal_title：Journal of critical care

authors： Broch O,Renner J,Gruenewald M,Meybohm P,Höcker J,Schöttler J,Steinfath M,Bein B

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:The prevalence and clinical significance of lactic acidosis in diabetic ketoacidosis (DKA) are understudied. The objective of this study was to determine the prevalence of lactic acidosis in DKA and its association with intensive care unit (ICU) length of stay (LOS) and mortality. METHODS:Retrospective, observ...

journal_title：Journal of critical care

authors： Cox K,Cocchi MN,Salciccioli JD,Carney E,Howell M,Donnino MW

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Early rehabilitation in the intensive care unit (ICU) improves patients' physical function. Despite reports of using commercially available interactive video game systems for rehabilitation, there are few data evaluating feasibility and safety as part of routine in-patient rehabilitation, particularly in the...

journal_title：Journal of critical care

authors： Kho ME,Damluji A,Zanni JM,Needham DM

更新日期：2012-04-01 00:00:00

abstract：PURPOSE:We wanted to identify the importance of the duration of invasive ventilation and of renal replacement therapy for short-term prognosis of surgical patients treated in an intensive care unit (ICU). METHODS:We analyzed adult patients (n = 1462) who had an ICU length of stay of more than 4 days and who were follo...

journal_title：Journal of critical care

authors： Schneider CP,Fertmann J,Miesen J,Wolf H,Flexeder C,Hofner B,Küchenhoff H,Jauch KW,Hartl WH

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to refine and validate an automatic risk of unplanned readmission (Stability and Workload Index for Transfer, or SWIFT) calculator in a prospective cohort of consecutive medical intensive care unit (ICU) patients in a teaching hospital with comprehensive electronic medical records (E...

journal_title：Journal of critical care

authors： Chandra S,Agarwal D,Hanson A,Farmer JC,Pickering BW,Gajic O,Herasevich V

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:The purpose of this study is to determine if temperature extremes are associated with reduced heart rate variability (HRV) and "cardiac uncoupling." MATERIALS AND METHODS:This was a retrospective, observational cohort study performed on 278 trauma intensive care unit admissions that had continuous HR, cardiac ...

journal_title：Journal of critical care

authors： Mowery NT,Morris JA Jr,Jenkins JM,Ozdas A,Norris PR

更新日期：2011-10-01 00:00:00

abstract：INTRODUCTION:Patients with septic shock often receive intravenous vasopressor infusions, with little evidence available to guide their titration. We surveyed Canadian intensivists to document self-reported vasopressor titration strategies for patients with septic shock. METHODS:We identified Canadian intensivists cari...

journal_title：Journal of critical care

authors： Lamontagne F,Cook DJ,Adhikari NKJ,Briel M,Duffett M,Kho ME,Burns KEA,Guyatt G,Turgeon AF,Zhou Q,Meade MO

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:Closed endotracheal suctioning (CES) may impact ventilator-associated pneumonia (VAP) risk by reducing environmental contamination. In developing countries where resource limitations constrain the provision of optimal bed space for critically ill patients, CES assumes greater importance. MATERIALS AND METHODS:...

journal_title：Journal of critical care

authors： David D,Samuel P,David T,Keshava SN,Irodi A,Peter JV

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:Although 4% albumin is associated with increased mortality in patients with traumatic brain injury (TBI), evidence concerning the safety of synthetic colloids is lacking. We aimed to determine if there is an association between synthetic colloids and mortality in patients with severe TBI. MATERIALS AND METHODS...

journal_title：Journal of critical care

authors： Sekhon MS,Dhingra VK,Sekhon IS,Henderson WR,McLean N,Griesdale DE

更新日期：2011-08-01 00:00:00

abstract：PURPOSE:The prognostic value of hyperlactatemia in septic shock is unquestionable. However, as current definitions do not include hyperlactatemia as a mandatory criterion, some hypotensive patients may be diagnosed as having septic shock despite exhibiting normolactatemia. The significance of persistent sepsis-induced ...

journal_title：Journal of critical care

authors： Hernandez G,Castro R,Romero C,de la Hoz C,Angulo D,Aranguiz I,Larrondo J,Bujes A,Bruhn A

更新日期：2011-08-01 00:00:00

abstract：PURPOSE:The aim of the present study was to explain why extravascular lung water index (EVLWI) is higher and why global end-diastolic blood volume index (GEDVI) is lower in young children when measured with the PiCCO system (Pulsion, Munich, Germany). MATERIALS AND METHODS:We pooled available data from literature from...

journal_title：Journal of critical care

authors： Lemson J,Merkus P,van der Hoeven JG

更新日期：2011-08-01 00:00:00

abstract：PURPOSE:The study aimed to compare hemoglobin (Hb) values determined using the portable HemoCue system (HemoCue Hb 201+; HemoCue AB, Ängelholm, Sweden) with laboratory Hb level determination. MATERIALS AND METHODS:Adult patients hospitalized in our surgical intensive care unit who required an Hb level determination we...

journal_title：Journal of critical care

authors： Seguin P,Kleiber A,Chanavaz C,Morcet J,Mallédant Y

更新日期：2011-08-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the causes, incidence, and impact on outcome of admission hyperlactatemia in patients admitted to a general medical intensive care unit (ICU). METHODS:A retrospective cohort study was done in an 8-bed general ICU of tertiary care hospital over 15 months. Data regarding pat...

journal_title：Journal of critical care

authors： Juneja D,Singh O,Dang R

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:Low tidal volume (LTV) ventilation reduces mortality in patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). This study investigates adherence of intraoperative LTV and whether patient outcomes were different with or without continued intraoperative LTV ventilation in patients wi...

journal_title：Journal of critical care

authors： Chaiwat O,Vavilala MS,Philip S,Malakouti A,Neff MJ,Deem S,Treggiari MM,Wang J,Lang JD

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:This study compared clinical outcomes associated with exposure to pulmonary artery catheters (PACs), central venous catheters (CVCs), arterial pressure waveform analysis for cardiac output (APCO), or no central monitoring (NCM) in patients with shock. MATERIALS AND METHODS:We assessed 6929 consecutive patients...

journal_title：Journal of critical care

authors： Hata JS,Stotts C,Shelsky C,Bayman EO,Frazier A,Wang J,Nickel EJ

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:The aim of this study was to validate and compare the performance of the Acute Physiology and Chronic Health Evaluation (APACHE) IV in the Dutch intensive care unit (ICU) population to the APACHE II and Simplified Acute Physiology Score (SAPS) II. MATERIALS AND METHODS:This is a prospective study based on data...

journal_title：Journal of critical care

authors： Brinkman S,Bakhshi-Raiez F,Abu-Hanna A,de Jonge E,Bosman RJ,Peelen L,de Keizer NF

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:The objectives of this study were to compare patients' energy expenditure (EE) during pressure support (PS) and T-tube (TT) weaning from mechanical ventilation (MV) through indirect calorimetry (IC) and to crosscheck these findings with the results calculated using Harris-Benedict (HB) equation. METHODS:Thi...

journal_title：Journal of critical care

authors： dos Santos LJ,Hoff FC,Condessa RL,Kaufmann ML,Vieira SR

更新日期：2011-02-01 00:00:00

abstract：HYPOTHESIS:As vasopressin is a small peptide, its sieving coefficient (SC) and clearance (CL) during continuous renal replacement therapy may be intermediate to those for urea and β2 microglobulin (commonly used markers for small- and middle-molecular weight solutes, respectively). METHODS:A prospective, minimal-risk ...

journal_title：Journal of critical care

authors： Baird JS

更新日期：2010-12-01 00:00:00

abstract：PURPOSE:The aims of the study were to assess opinions of caregivers, families, and patients about involvement of families in the care of intensive care unit (ICU) patients; to evaluate the prevalence of symptoms of anxiety and depression in family members; and to measure family satisfaction with care. MATERIALS AND ME...

journal_title：Journal of critical care

authors： Garrouste-Orgeas M,Willems V,Timsit JF,Diaw F,Brochon S,Vesin A,Philippart F,Tabah A,Coquet I,Bruel C,Moulard ML,Carlet J,Misset B

更新日期：2010-12-01 00:00:00

abstract：PURPOSE:Mortality in severe sepsis and septic shock (SS/SS) remains high. Surviving Sepsis Campaign (SSC) guidelines were published in 2004 with the goal of improving outcomes in SS/SS. We tested the hypothesis that adherence to SSC guidelines and management of patients with SS/SS were influenced by physician specialty...

journal_title：Journal of critical care

authors： Djurkovic S,Baracaldo JC,Guerra JA,Sartorius J,Haupt MT

更新日期：2010-12-01 00:00:00

abstract：:Postobstructive pulmonary edema (POPE; also known as negative pressure pulmonary edema) is a potentially life-threatening complication in which pulmonary edema occurs shortly after the relief of an upper airway obstruction. The incidence of POPE has been reported to be as high as 1 in 1000 general anesthetic cases and...

journal_title：Journal of critical care

authors： Udeshi A,Cantie SM,Pierre E

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:Rescue organ offers may help to overcome the organ shortage. However, because of initial poor liver function, the recipient may develop a severe lung injury with the requirement for higher positive end-expiratory pressure (PEEP) levels to achieve adequate oxygenation. Positive end-expiratory pressure has been a...

journal_title：Journal of critical care

authors： Saner FH,Olde Damink SW,Pavlaković G,Sotiropoulos GC,Radtke A,Treckmann J,Beckebaum S,Cicinnati V,Paul A

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:The aim of this study was to determine the incidence of pressure ulcers (PUs) in ventilated patients in all intensive care units (ICUs) in Granada (Spain) and identify risk factors for their development. MATERIALS AND METHODS:A prospective cohort study in 9 medical-surgical ICUs was conducted. Two hundred nine...

journal_title：Journal of critical care

authors： Manzano F,Navarro MJ,Roldán D,Moral MA,Leyva I,Guerrero C,Sanchez MA,Colmenero M,Fernández-Mondejar E,Granada UPP Group.

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:This study was designed to determine the recompression strategy and the potential risk factors associated with the development of severe diving-related spinal cord decompression sickness (DCS). MATERIAL AND METHODS:Sixty-three injured recreational divers (52 men and 11 women; 46 +/- 12 years) presenting with s...

journal_title：Journal of critical care

authors： Gempp E,Blatteau JE

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:When radiologists are not available, chest radiographs (CXRs) of pediatric intensive care unit (PICU) patients are commonly interpreted by pediatric intensivists. We prospectively investigated the frequency of errors in CXR interpretation by pediatric intensivists and their impact on patient management. MATERI...

journal_title：Journal of critical care

authors： Nesterova GV,Leftridge CA Jr,Natarajan AR,Appel HJ,Bautista MV,Hauser GJ

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:A nationwide increase in the rate and severity of Clostridium difficile-associated disease may reflect infection with a virulent strain characterized by polymerase chain reaction as ribotype 027 (NAP1/B1). HYPOTHESIS:The high prevalence of ribotype 027 at our institution would allow investigation of the ris...

journal_title：Journal of critical care

authors： Gasperino J,Garala M,Cohen HW,Kvetan V,Currie B

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:The purpose of this retrospective study was to evaluate cardiac troponin-I (cTnI) as a 28-day mortality prognosticator and predictor for a drotrecogin alfa (activated) (DrotAA) survival benefit in recombinant human activated Protein C Worldwide Evaluation in Severe Sepsis patients. METHODS:Cardiac troponin-I w...

journal_title：Journal of critical care

authors： John J,Woodward DB,Wang Y,Yan SB,Fisher D,Kinasewitz GT,Heiselman D

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:The response to inhaled nitric oxide (iNO) is inconsistent in patients with acute respiratory distress syndrome (ARDS). We sought to determine whether the response to iNO, defined as 20% Pao(2)/Fio(2) increase from baseline, depends on the level of cardiac natriuretic peptides. MATERIALS AND METHODS:This is a ...

journal_title：Journal of critical care

authors： Treggiari MM,Bendjelid K,Yanez ND,Heidegger CP,Suter PM,Romand JA

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:The aim of the study was to assess the ability of plasma neutrophil gelatinase-associated lipocalin (pNGAL) to predict acute kidney injury (AKI) in adult intensive care unit (ICU) patients. METHODS:All consecutives patients admitted to 3 ICUs were enrolled in this prospective-observational study. Plasma neutro...

journal_title：Journal of critical care

authors： Constantin JM,Futier E,Perbet S,Roszyk L,Lautrette A,Gillart T,Guerin R,Jabaudon M,Souweine B,Bazin JE,Sapin V

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Studies investigating the metabolic effects of citrate-based substitution fluids are lacking. This study aims to compare the effect of citrate- vs bicarbonate-based substitution fluid used during continuous venovenous hemofiltration (CVVH) for acute kidney injury on acid-base balance and electrolytes in crit...

journal_title：Journal of critical care

authors： Aman J,Nurmohamed SA,Vervloet MG,Groeneveld AB

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:The aim of the study was to investigate possible associations between different heart rate variability (HRV) indices and various biomarkers of inflammation in 45 septic patients. MATERIALS AND METHODS:We daily assessed HRV in the time domain (SD of RR intervals [SDNN]), frequency domain (low [LF], high frequen...

journal_title：Journal of critical care

authors： Papaioannou VE,Dragoumanis C,Theodorou V,Gargaretas C,Pneumatikos I

更新日期：2009-12-01 00:00:00